<ul><li><b><i>Lessertia frutescens</i></b><b>, </b><b><i>Protea venus</i></b><b>, and</b><b><i> Leucadendron xanthoconus</i></b><b> NMR</b>: This dataset contains 1D and 2D NMR spectroscopy data for compounds isolated from <i>L. frutescens</i>, <i>P. venus</i>, and <i>L. xanthoconus</i>. The spectra were recorded using a Bruker 400 MHz FT-NMR spectrometer equipped with a 5mm BBO probe at the Cape Peninsula University of Technology Chemistry Department.</li><li><b>CPUT Study</b>: This dataset includes the results from biological assays conducted to evaluate the bioactivity of the isolated compounds, contributing to the assessment of their potential biological applications.</li></ul><p></p>