Cape Peninsula University of Technology
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Biochemical analysis and Microrna profiling in a high glucose in vitro model with resveratrol intervention_ datasets

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posted on 2024-04-02, 08:07 authored by Abegail TshivhaseAbegail Tshivhase

This research does not have questionnaires and interview data. All the data generated were from the independent biochemical experiments. This was an in vitro study, where HepG2 cells were exposed to high glucose and resveratrol for 48 and 72 hours. The research outlined the potential therapeutic effects of resveratrol on varying molecular pathways i.e. Inflammation, Oxidative stress, Apoptosis, and glucose metabolism, contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). It also included epigenetic factors by quantification of microRNAs linked to T2DM pathogenesis in HepG2 cells exposed to high glucose and resveratrol.

Funding

South African Medical Research Council (SAMRC), with funds from National Treasury under its Economic Competitiveness and Support Package (MRC‐RFA‐UFSP‐01‐2013/VMH Study) and South African National Research Foundation (SANRF) (Grant no. 115450).

History

Is this dataset for graduation purposes?

  • Yes

Supervisor email address

RAGHUBEERS@cput.ac.za

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    Cape Peninsula University of Technology

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